Explains the concept of the gut-brain axis, and its implications for health and disease. Describes how microbes and their metabolites communicate with the body and the brain. Explains how the microbiome-gut-brain axis influences the development of neurodegenerative, neuropsychiatric, and neurodevelopmental disorders. Describes how microbial metabolites regulate immune and metabolic pathways in the body, and how this may impact risk of allergies, autoimmune diseases, obesity and diabetes. Explains how the ecology of the oral microbiome impacts both gut and systemic health; discusses implications for modern-day oral healthcare. Lists potential microbial and gut health disruptors, as well as therapeutic strategies to improve gut and brain health (to become “ecosystem engineers”). Describes ways in which the highly complex gut-brain scientific research has been oversold and misinterpreted by the lay press. Identifies red flags of “pseudoscience” to become a healthy skeptic. Describes how the information in this course can be utilized to improve patient care and patient outcomes.

Describes the stages, cycling, and circadian rhythms of sleep. Cites evidence connecting sleep deprivation and sleep disorders to heart disease, stroke, diabetes, and dementia. Lists the major sleep medications with their uses and adverse effects. Describes the connection between dental pain and sleep disruption. Cites the diagnostic criteria, symptoms, course, and treatment for the major sleep disorders. Describes how the information in this course can be utilized to improve patient care and patient outcomes. Describes, for this course, the implications for dentistry, mental health, nursing, and other healthcare professions.

Explains the current state of pain management in the United States. Describes the multidisciplinary approach to pain management. Reviews the 23 different pain management modalities currently available. Describes steps to create a comprehensive pain management plan. Lists the five key coping skills for helping chronic pain patients. Discusses treatment options for chronic dental and facial pain. Describes how the information in this course can be utilized to improve patient care and patient outcomes. Describes the implications for dentistry, mental health, and other health professions.